Remplir® B12 & Magnesium Supplement

90-day supply
$31.58 $37.89
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Remplir is a vitamin B12 and magnesium supplement with whole-body benefits: healthy energy levels, metabolism, brain function, mental health, nerve and muscle function, and much more.* 

  • Contains vitamin B12 and chelated magnesium for optimal absorption and bioavailability.* 
  • Designed for: Anyone searching for a high-quality vitamin B12 and magnesium supplement. Adults taking acid-reducing medications, metformin, or other medications that may deplete vitamin B12 and magnesium levels. Vegetarians and vegans. Adults 60+. 

Independently tested and certified by NSF® International. Manufactured in the USA in a GMP-compliant facility.


Take one tablet per day with food, or as recommended by your healthcare provider.   

Frequently Purchased Together

How is Remplir different?
Remplir is a unique supplement, combining two nutrients with benefits for whole-body health: vitamin B12 and magnesium.* But the form of these nutrients matters. We’ve chosen a blend of two forms of vitamin B12: methylcobalamin and cyanocobalamin , as well as magnesium bisglycinate (a chelated form of magnesium) for optimal absorption and bioavailability.*

Plus, Remplir is the only vitamin B12 and magnesium supplement that is independently tested and certified by NSF® International for content accuracy and purity, so you know exactly what you’re getting.

Who is likely to benefit from Remplir?
Remplir can be beneficial for:

  • Adults taking an acid-reducing medication (Prilosec, Nexium, etc.), metformin, or other medications that deplete vitamin B12 and magnesium levels in the body.*
  • Adults 60+.
  • Vegetarians and vegans.
  • Anyone who does not get enough vitamin B12 and magnesium from diet alone.
  • Are there any side effects from taking Remplir?
    No. There are no expected side effects from Remplir.
    Can I take other nutritional supplements along with Remplir?
    Yes. You can take Remplir along with most multivitamins and other nutritional supplements. Do not take with other supplements that contain large doses of vitamin B12 or magnesium unless advised by your healthcare provider.
    Does Remplir interact with any prescription medications?

    The list below includes some of the more common potential interactions. This is not meant to be a comprehensive list or take the place of advice from your healthcare provider. As with any dietary supplement, discuss with your pharmacist and/or healthcare team to determine whether Remplir can be taken along with your medications.

    Antibiotics: Taking magnesium along with antibiotics can decrease the absorption and effectiveness of the antibiotic. Depending on which antibiotic is prescribed, you may need to separate Remplir from the antibiotic, as indicated below.

  • Tetracycline antibiotics (doxycycline, minocycline, demeclocycline): Separate by 4 hours.  
  • Quinolone (Ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin (Levaquin), Moxifloxacin (Avelox)): Separate by 6 hours.

    Oral Bisphosphonates (i.e., alendronate (Fosamax), etidronate (Didronel), risedronate (Actonel), ibandronate (Boniva), tiludronate (Skelid)): Magnesium can decrease the absorption of these medications. Separate by 2 hours.