methylated folate and vitamin B12 supplement designed to provide nutrient support while taking methotrexate
a nutritional supplement designed to provide nutrient support during methotrexate therapy.
A nutritional supplement containing methylated folate and methylated b12
Independently tested and certified by NSF® International. Manufactured in the USA in a GMP-compliant facility.
A supplement recommended for those taking methotrexate, or for anyone who needs extra folate or vitamin B12.
MTX Advanced Support is designed to provide nutrient support for those taking methotrexate, or for anyone that needs extra folate or vitamin B12.*
methylated folate and vitamin B12 supplement designed to provide nutrient support while taking methotrexate
a nutritional supplement designed to provide nutrient support during methotrexate therapy.
A nutritional supplement containing methylated folate and methylated b12
Independently tested and certified by NSF® International. Manufactured in the USA in a GMP-compliant facility.
A supplement recommended for those taking methotrexate, or for anyone who needs extra folate or vitamin B12.
MTX Advanced Support is designed to provide nutrient support for those taking methotrexate, or for anyone that needs extra folate or vitamin B12.*

MTX Advanced Support® B12 & Folate Supplement

90-day supply
$41.05 $49.47
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MTX Advanced Support is a methylated folate and vitamin B12 supplement designed to provide nutrient support while taking methotrexate.* 

  • Contains methylated vitamin B12 and methylated folate, the bioactive, ready-to-use forms.  
  • Maintains healthy folate levels and safeguards vitamin B12 levels, as high-dose folate may mask low vitamin B12 levels.* 
  • Recommended for those taking methotrexate, or for anyone who needs extra folate or vitamin B12.* 

    Independently tested and certified by NSF® International. Manufactured in the USA in a GMP-compliant facility.

    SUGGESTED USE

    Take one tablet per day or as recommended by your healthcare provider.

    Frequently Purchased Together

    FAQs
    How is MTX Advanced Support different?
  • Independently tested and certified. MTX Advanced Support is tested and certified by NSF® International for content accuracy and purity, so you know exactly what you’re getting.

  • Formulated specifically for those taking methotrexate. MTX Advanced Support helps maintain healthy folate levels and safeguards vitamin B12 levels, as high dose folate may mask low vitamin B12 levels.*

  • Quality you can trust. MTX Advanced Support is manufactured in the USA in a cGMP compliant facility.
    • Why folate and vitamin B12?
    Methotrexate may decrease folate levels in the body. Taking a high-quality folate supplement can help maintain healthy folate levels during methotrexate therapy.*

    High-dose folate supplementation can “mask” low vitamin B12 levels, so experts recommend taking a vitamin B12 supplement along with folate.*

    Who can benefit from MTX Advanced Support?
    MTX Advanced Support is designed to provide nutrient support for those taking methotrexate, or for anyone that needs extra folate or vitamin B12.*
    Are there any side effects from taking MTX Advanced Support?
    No. There are no expected side effects from taking MTX Advanced Support.
    How long should I take MTX Advanced Support?
    We recommend taking MTX Advanced Support while you are on methotrexate therapy, or as directed by your healthcare provider.
    Can I take MTX Advanced Support with other nutritional supplements?
    Yes. You can take MTX Advanced Support along with most multivitamins or other nutritional supplements. Do not take MTX Advanced Support with other single nutrient supplements that contain large doses of folic acid, folate, or vitamin B12, unless otherwise directed by your healthcare provider.
    Does MTX Advanced Support interact with prescription medications?
    The list below includes some of the more common potential interactions. This is not meant to be a comprehensive list or take the place of advice from your healthcare provider. As with any dietary supplement, discuss with your pharmacist and/or healthcare team to determine whether MTX Advanced Support can be taken with your medications.

    Pyrimethamine (Daraprim): Folate may decrease the antiparasitic effects of this medication.

    Seizure medications (phenytoin (Dilantin), primidone (Mysoline), phenobarbital (Luminal)): Folate may reduce the effects of these medications and increase seizure risk.

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